Products 2
神经刺激疗法
开放式创新
凭借开放式创新理念，我们将外部新技术引入我们自己的创新过程，并促进信息共享和协作以创造价值。
为了满足中国日益增长的医疗保健需求，我们与各种世界一流的创新机构——研究机构、医生和其他公司——合作，以创建创新生态系统，并将合作转化为可实现的成果。
开放式创新流程以下是 MaxNova 产品的开放式创新流程。我们正在研究改变生活的治疗方法，以建立产品管线和改善病人神经系统的健康。
加快创新和产品开发 - 增加竞争优势
- 降低成本、风险和产品周期
- 互惠互利，共享知识、人才和基础设施
我们在识别关键创新和外部伙伴方面的管理能力和方法，使我们能够整合新颖而有前景的技术。凭借在新产品开发和监管审批方面的丰富资源，我们的中国团队与全球人才密切合作，确保产品顺利本地化。此外，通过掌握产品的市场适应性和市场进入策略，我们的团队可以有效地将技术从概念转移到市场。
产品组合
侵入性神经刺激疗法
脑深部刺激是一种主要用于治疗帕金森症的外科手术，来缓解帕金森相关的运动障碍症状，例如震颤、强直和僵硬。 随着帕金森导致的全球残疾和死亡人数的增加，人们迫切需要新的治疗途径。 近来，在电极和电池设计、闭环和按需刺激方面取得的技术突破将改善脑深部刺激的临床效果。
脊髓刺激广泛用于控制各种原因引起的慢性疼痛，例如慢性腿部或手臂疼痛、糖尿病性神经病变、背部手术失败综合征和蛛网膜炎等。 大量的脊髓刺激临床试验正在进行中——这表明该领域正在迅速发展，并且市场对技术改进的需求很高。
迷走神经刺激一直是控制癫痫患者癫痫发作的重要治疗方法。 与涉及脑部手术的其他类型的癫痫手术不同，迷走神经刺激通过颈部的迷走神经起作用以减少癫痫发作。 包括闭环和非侵入性技术在内的一些最新技术创新会有助于提高临床疗效，并最大限度地减少副作用。
反应性神经刺激是另一种癫痫治疗方法，该疗法可监测大脑活动并在检测到癫痫发作时，及时提供电刺激。 大约 30% 的癫痫患者对药物治疗有抵抗力，这使得迷走神经刺激或反应性神经刺激成为他们理想的治疗方法，特别是如果癫痫发作起源于大脑深处或靠近控制关键功能的大脑区域。
非侵入性神经刺激疗法
经颅磁刺激是一种非侵入性疗法，它使用电磁刺激来改善抑郁症或偏头痛的症状。 作为一种非侵入性治疗，经颅磁刺激的优点包括：不需要麻醉，门诊治疗即可，通常耐受性良好。 很多研究在尝试使用经颅磁刺激治疗其他疾病，如阿尔茨海默症、帕金森症、中风等。
经皮神经电刺激是一种非侵入性的止痛方法。 经皮神经电刺激装置通常小巧便携，可以在家中或外出使用，任何需要缓解疼痛的时候都可以使用。 经皮神经电刺激可以短期缓解由多种疾病引起的疼痛和肌肉痉挛，包括关节炎、经期疼痛、骨盆疼痛、运动损伤等。
Open Innovation
With an Open Innovation philosophy, we bring external ideas and technologies into our own innovation process and allow increased information sharing and collaboration to create value.
In an effort to serve China’s growing healthcare needs, we partner with various pools of world-class innovation – research institutions, physicians, and other companies – to empower an innovation ecosystem and translate collaboration into actionable outcomes.
Our Open Innovation WorkflowWith our Open Innovation approach, below is the life cycle of a product at MaxNova. As the development process proceeds, the product moves down the pipeline. Through our pipeline, we are researching life-changing treatments to improve the health of nervous system.
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Accelerate the speed of innovation and new product development process
- Increase competitive advantages
- Reduce cost, risk, and timescales
- Mutually beneficial with shared knowledge, talents, and infrastructures
Our proven managerial capabilities and approaches in seeking and collaborating with external partners enable us to find novel, high-promise technologies with agility. Highly experienced in new product development and China market entry strategies, our China-based team closely works together with global talents to ensure smooth product localization. Moreover, with a good grasp of the fit between the China business environment and the new product, our team can efficiently move technology from concept to the marketplace.
Product Portfolio
Invasive Neurostimulation Therapies
DBS is a major surgical procedure to treat disabling neurological symptoms of PD, such as tremors, rigidity, and stiffness. With the global rise of disability and death due to PD, novel therapeutic avenues are in great demand. Recent breakthroughs in electrode and battery designs, close-loop and on-demand stimulation would improve the clinical outcome of DBS.
SCS is widely used to help manage chronic pain caused by various conditions such as chronic leg or arm pain, diabetic neuropathy, failed back surgery syndrome, and arachnoiditis. A large number of clinical trials of SCS are underway – suggesting that this field is rapidly growing and there is a high demand for improved technologies.
VNS has been a valuable treatment to control seizures for people with epilepsy. Unlike other types of epilepsy surgery, which involve brain operations, the VNS works through the vagus nerve in the neck to reduce seizures. Some recent developments including close-loop and non-invasive techniques may improve clinical efficacy and minimize side effects.
RNS is another epilepsy treatment that monitors brain activity and delivers electrical stimulation when a seizure is detected. About 30% of epilepsy patients are resistant to medical therapy, making VNS or RNS desirable treatments for them, especially if seizures originate deep in the brain or close to brain regions that control critical functions.
Non-Invasive Neurostimulation Therapies
TMS is a non-invasive procedure that uses magnetic stimulation to improve symptoms of depression or migraine. As a non-invasive treatment, TMS has the advantages that it is an outpatient service that does not require anesthesia and is usually well tolerated. Research is also ongoing to study TMS to treat other conditions such as Alzheimer’s disease, Parkinson’s disease, stroke, etc.
TENS is a non-invasive method for pain relief. TENS unit is usually small and portable and could be used at home or away, anytime pain relief is needed. TENS may provide short-term relief of pain and muscle spasms caused by a wide range of conditions including arthritis, period pain, pelvic pain, sports injuries, etc.
